Chromatography system

Chromatography system

QuantaSep Trusty Chromatograph system
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QuantaSep Trusty Chromatograph system

Sepragen chromatograph is widely used in the separation and purification of biological macromolecules, has served more than 40 FDA approved drug research and development projects, effectively support radial chromatography process, the application range covers lab, pilot, production scale purification research, fully meet customer needs.

Products are divided into 3 series according to their characteristics.

  • Description

  • Brand

  • Reference

Overview：

Sepragen chromatograph is widely used in the separation and purification of biological macromolecules, has served more than 40 FDA approved drug research and development projects, effectively support radial chromatography process, the application range covers lab, pilot, production scale purification research, fully meet customer needs.

Products are divided into 3 series according to their characteristics.

1) QuantaSep Trusty Series:

General configuration series.

2) QuantaSep Adept two-channel series:

A set of chromatograph is configured with 2-3 sets of flow paths, and users can switch between lab, pilot and production scale according to actual needs, which is equivalent to 2-in-1 or 3-in-1 models.

3) QuantaSep Adept single use:

In order to avoid the trouble of cleaning and cleaning verification, the single use flow path SU (Single Use) series is designed. The flow path design of the system is flexible and can be disassembled for easy cleaning and disinfection.

All series meet the requirements of cGMP production conditions, all support the sample forward, reverse and bypass 3 inflow modes, so that the product and the resin more fully combined. There is also a unique pre-filtration function, automatic bubble eject function and leakage monitoring function to make the purification process more efficient. QuantaSep software complies with 21CFR, Part11, automatically generates GMP reports.

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QuantaSep Trusty（part of representative products）

Catalog #

Description

50-0100-0000-TS

QuantaSep Trusty 100 Chromatography System with:
• Dual pump gradient (5%-95%) capability
• 12 user selectable buffers
• 3 user selectable columns with forward/reverse/bypass mode,
• Dual UV (280nm, 254nm), conductivity, temperature, pH, pressure, air sensors
• 10 user selectable fractions with fraction collect capability, Sanitary design,
• Flowrate Range: 1-100 ml/min, ± 3 %

Maximum Pressure: 100 psi, and includes Sanitary External Tubing Set, All-in-One PC, software & cables

50-1000-0R00-TS

QuantaSep Trusty 1000 Chromatography System with:
• Dual pump gradient (5%-95%) capability,
• 12 user selectable buffers,
• 3 user selectable columns with forward/reverse/bypass mode,
• Dual UV (280nm, 254nm), conductivity, temperature, pH, pressure, air sensors,
• 10 user selectable fractions with fraction collect capability, Sanitary design,
• Flowrate Range: 10-1000 ml/min, ± 3%,

Maximum Pressure: 100 psi, All-in-One PC, software & cables

50-1000-LX00-TS

QuantaSep Trusty LX Chromatography System - Functions as a dual flowrate sanitary system. Upper portion is Low Flow: 100 ml/min gradient system. Lower portion is high Flow: 1000 ml/min gradient system.
Both high and low flow systems feature:
• Dual pump gradient (5%-95%) capability;
• 6 inlets pump A, 6 inlets Pump B,
• 3 user selectable columns with forward/reverse/bypass mode
• Dual UV (280nm, 254nm), conductivity, temperature, pH, pressure, and air sensors;
• 10 user selectable fractions with fraction collector option.

Maximum Pressure: 100 psi, and includes Sanitary External Tubing Set, All-in-One PC, software & cables. Requires External Tubing for 1000 Mode

A set of chromatograph is configured with 2 sets of flow paths, and users can switch between lab scale, pilot scale according to actual needs

Order list：

QuantaSep trusty

 

QS100

QS1000

QS1000LX

QS1800

QS5000

QS10000

Cat.No

50-0100-0000-TS

50-1000-0R00-TS

50-1000-LX00-TS

50-1800-0R00-TS

50-5000-0000-TS

50-10000-0000-TS

Flow rate

1 -100 mL/min

10 -1000 mL/min

1 -100 mL/min&

10 -1000 mL/min

20 -

1800mL/min

50 mL/min -

5 L/min

100mL/min-

10 L/min

inlet

12

12

12*2

12

8

8

column

3

3

3*2

3

1

1

outlet

10

10

10*2

10

6

6

Dead volumn

7 mL

120 mL

lower:18 mL upper:120 mL

120 mL

~650 mL

1.2 L

size

21"x26" x15"

21"x26" x15"

21"x26" x15"

21"x26" x15"

22"x27" x46.5"

22"x27" x46.5"

gradient

5-95%

5-95%

5-95%

5-95%

5-95%

5-95%

pressure

100psi

50psi

50psi

50psi

50psi

50psi

Flow path

1/16"

1/4"

lower:1/16"

upper:1/4"

3/8"

1/2"

5/8"

Chemical compatibility

1M NaOH 19%Alcohol

Operating temperature

4~25℃

Wet material

Flow path

Silicone, polyethylene and polypropylene

Valve / accessory

polypropylene

diaphragm

Polytetrafluoroethylene

sensors

Glass, quartz, 316L stainless steel

Component specification

UV

280 nm 0~2 Au

254 nm 0~2 Au (Optional)

conductivity

0~200mS/cm

pH

1~14

Leak sonsor

5 mL

Bubble size

> 0.20"

Based in California, Sepragen Corporation provides the biotechnology and nutraceutical industries with breakthrough products and processes to meet their process development and manufacturing needs.

Sepragen Corporation was founded in 1985 by Vinit Saxena, the inventor of radial flow chromatography technology. The company currently has 16 core patented technologies. Its main products include chromatography columns and their filling systems, chromatography systems, chromatography resins, bioreactors and Other accessories etc. Since its establishment, the company has cooperated with major well-known companies in North America, Europe, Australia and Asia and has received widespread praise. 

1）Saxena Vinit．Chromatography column using horizontal flow，US19850794727A

2）Saxena Vinit, Pinole, Calif. Chromatography column using horizontal flow，US19860869295A

3）Saxena Vinit, Pinole, Calif. Chromatography system using horizontal flow columns，US19880207896A

4）Saxena Vinit、 Saxena Renu、 Zuffi David. Axial and radial flow columns with inflatable seals to facilitate packing and unpacking，US201213723959A

5）Saxena Vinit、Saxena Renu、Zuffi David. Pre-packed, sealed radial flow chromatography column.US201615336619A

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