AbioSUS disposable bioreactor is integrated with a stainless steel tank, a disposable reaction bag, and a temperature control unit (TCU), and is available in 50L, 200L, and 500L , 1000L, 2000L different specifications of cultivation needs. The design principles of traditional stirred bioreactors are maintained, including specific height ratios and optimized stirring paddle positions, providing optimal cell viability, performance and scalability from process development to production. It can be widely used in multi-process upstream cell culture in the fields of antibodies, vaccines, cell therapy/gene therapy and other fields.

AbioSUS Features

1. Opening and closing door, easy to load bag

2. Water circulation in full jacket realizing thermal control in door and vessel to improve the consistency of micro-environment

3. Novel dual-impeller for different scale cell culture

4. Uses the latest probe sensor technology in single-use or autoclavable probes

5. Integrated TCU (Thermo Circulator Unit), no need for extra heating device

6. Dual-sparger with gas outlet selection. Improve kLa, optimize pH control, and reduce the formation of bubbles

7. Audit trial, 21 CFR part 11 compliant. Support analog in and out. Integrated to SCADA software by OPC connectivity

Control tower-AbioControl

1. Stay flexible and optimize space; Ensure an optimized system configuration and investment that match dedicated needs. Support working volume range from 50L to 2000L

2. 18.5 inch touch screen operator interface, 4 levels user management (View, Operator, Engineer, Service) to minimize the risk during process

3. Multiple control loops for pH, temperature, DO, stir and more. Adjustable process control strategy. Intact real-time trend. An intuitive and user-friendly interface reduces the risk of operator error and cuts training time

4. Compatible with serial cascading and parallel cascading control loops, which can be switched according todifferent control requirements to realize stable process control and ensure reproducibility

5. Expansibility (lnputs/Outputs); Connect to 3rd party through 4-20mA and Modbus. Such as variable speedtubing pumps, MFC, balance, exhaust gas sensors. Support multiple control software interaction and datatransmission

6. Modular design for easier incorporation in cleanroom or pilot facilities

AbioSUS single-usebioreactorTechnicalData

System specifications 

Liquid and gas additions

Process instrumentation